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This is why grapefruit is so dangerous for so many medicines. Those medicines take bioavailability into account and can be a massive dose in some cases. Grapefruit keeps the same mechanism that lowers effective dosage busy, substantially increasing the effective dose - straight into overdose territory in some cases.
This is why grapefruit is so dangerous for so many medicines. Those medicines take bioavailability into account and can be a massive dose in some cases. Grapefruit keeps the same mechanism that lowers effective dosage busy, substantially increasing the effective dose - straight into overdose territory in some cases.